Buscar
Mostrando ítems 1-10 de 109
Histamine modulates γδ-T lymphocyte migration and cytotoxicity, via Gi and Gs protein-coupled signalling pathways
(Wiley Blackwell Publishing, Inc, 2010-11)
The biogenic amine, histamine plays a pathophysiological regulatory role in cellular processes of a variety of immune cells. This work analyses the actions of histamine on γδ-T lymphocytes, isolated from human peripheral ...
NetMHCstab – predicting stability of peptide–MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery
(Wiley, 2014-01)
Major histocompatibility complex class I (MHC-I) molecules play an essential role in the cellular immune response, presenting peptides to cytotoxic T lymphocytes (CTLs) allowing the immune system to scrutinize ongoing ...
Follicular CD8 + T Cells : Origin, Fuction and Importance During HIV Infection
(Frontiers Research FoundationInmunovirologíaLausana, Suiza, 2023)
Doramectin induced cytotoxic and genotoxic effects on bovine peripheral lymphocytes and cumulus cells in vitro
(Taylor & Francis, 2019-02)
The effect of doramectin (DOR) was tested on two experimental somatic bovine cells in vitro: peripheral lymphocytes (PL) and cumulus cells (CC). The cytotoxicity and genotoxicity of DOR were assessed using 3-(4,5-dimethy ...
Cytotoxic effect of potato aspartic proteases (StAPs) on Jurkat T cells
(Elsevier Science, 2009-10-13)
StAPs are potato aspartic proteases with cytotoxic activity against plant pathogens and spermatozoa. StAPs cytotoxic activity is selective, since these proteins do not exert toxic effect on plant cells and erythrocytes. ...
SYK-targeted dendritic cell-mediated cytotoxic T lymphocytes enhance the effect of immunotherapy on retinoblastoma
(Springer, 2018-01-25)
Purpose: Retinoblastoma (RB) is the most common primary intraocular tumor in children. Chemotherapy is currently the main method of RB treatment. Unfortunately, RB often becomes chemoresistant and turns lethal. Here, we ...
Development of a universa CTL-based vaccine for influenza
(Wiley, 2013-01)
In pursuit of better influenza vaccines, many strategies are being studied worldwide. An attractive alternative is the generation of a broadly cross-reactive vaccine based on the induction of cytotoxic T-lymphocytes (CTL) ...
Cancer immunotherapy–related adverse events: causes and challenges
(Springer, 2020-12)
Despite the success and ongoing promise of monoclonal antibody–targeted immune checkpoint inhibitor immunotherapy of advanced malignancies, in particular, antibodies directed against CTLA-4 and PD-1/PD-L1, the development ...
Short communication an interferon-γ ELISPOT assay with two cytotoxic T cell epitopes derived from HTLV-1 tax region 161-233 discriminates HTLV-1-associated myelopathy/tropical spastic paraparesis patients from asymptomatic HTLV-1 carriers in a peruvian population
(Mary Ann Liebert, 2011)
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic and progressive disorder caused by the human T-lymphotropic virus type 1 (HTLV-1). In HTLV-1 infection, a strong cytotoxic T cell (CTL) ...
Evaluacion citotoxica y clastogenicas en linfocitos humanos de un 5alfa, 8alfa-epidioxiesterolCytotoxic and clastogenic evaluation on human lymphocytes of a 5a, 8a - Epidioxysterol
(Universidad de Antioquia, Facultad de Ciencias Farmacéuticas y AlimentariasProductos Naturales MarinosMedellín, Colombia, 2021)